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Vincent-Wv JADDOE ; Johan-C DE JONGSTE ; Albert-Jvan DER HEIJDEN ; Aad-Van DER LUGT ; Cornelia-Mvan DUIJN ; Oscar-H FRANCO ; Albert HOFMAN ; MACKENBACH (Johan P.) ; Henriëtte-A Moll ; Hein RAAT ; Fernando RIVADENEIRA ; Eric-Ap STEEGERS ; Henning TIEMEIER ; André-G UITTERLINDEN ; Marinus-H VAN IIZENDOORN ; Frank-C VERHULST ; Department of Child and Adolescent Psychiatry. Sophia Children's Hospital. Erasmus Medical Center. Rotterdam. NLD |[BDSP. Notice produite par INIST-CNRS o8FsR0x8. Diffusion soumise à autorisation]. The Generation R Study is a population-based prospective cohort study from fetal life until adulthood. The study is designed to identify early environmental and g[...]Article
Andrew-E JAFFE ; M. DANIELE FALLIN ; Andrew-P FEINBERG ; Rafael-A IRIZARRY ; Hwajin LEE ; Jeffrey-T LEEK ; Peter Murakami ; Center for Epigenetics. Johns Hopkins School of Medicine. Baltimore. MD. USA |[BDSP. Notice produite par INIST-CNRS JlIR0xG8. Diffusion soumise à autorisation]. Background During the past 5 years, high-throughput technologies have been successfully used by epidemiology studies, but almost all have focused on sequence vari[...]Article
Gie KEN-DROR ; Fotios DRENOS ; Steve-E HUMPHRIES ; Mika KIVIMAKI ; Meena KUMARI ; Centre for Cardiovascular Genetics. Bhf Laboratories. The Rayne Building. Department of Medicine. Royal Free and University College Medical School. London. GBR |[BDSP. Notice produite par INIST-CNRS CIHGER0x. Diffusion soumise à autorisation]. Mendelian randomization studies on fibrinogen commonly use a single genetic variant as an instrument, but this may explain only a small proportion of the total ph[...]Article
Hwajin LEE ; Martin-J ARYEE ; Shannon BROWN ; Mdaniele FALLIN ; Jason-I FEINBERG ; Andrew-P FEINBERG ; Lynn-R GOLDMAN ; Julie HERBSTMAN ; Rafael-A IRIZARRY ; Andrew-E JAFFE ; Carolina MONTANO ; Rakel TRYGGVADOTTIR ; Frank-R WITTER ; Center for Epigenetics. Johns Hopkins School of Medicine. Baltimore. MD. USA |[BDSP. Notice produite par INIST-CNRS R0xmnmoG. Diffusion soumise à autorisation]. Background Gestational age at birth strongly predicts neonatal, adolescent and adult morbidity and mortality through mostly unknown mechanisms. Identification of [...]Article
Wei-Yen LIM ; Philip ENG ; . KHOON LEONG CHUAH ; Elaine LIM ; Alan NG ; Agus SALIM ; Adeline SEOW ; . SWAN SWAN LEONG ; Augustine TEE ; Ming TEH ; . TOW KEANG LIM ; . WEE TENG POH ; . YING CHEN ; Department of Respiratory and Critical Care Medicine. Tan Tock Seng Hospital. Singapore. SGP ; Saw Swee Hock School of Public Health. National University of Singapore. Singapore. SGP |[BDSP. Notice produite par INIST-CNRS JR0xG898. Diffusion soumise à autorisation]. The authors examined relations between reproductive factors and 5 estrogen pathway gene polymorphisms (CYP17 rs743572, CYP19A1 rs10046, ERbêta rs1256049, ERbêta r[...]Article
Genetic polymorphisms of clusterin gene are associated with a decreased risk of Alzheimer's disease.
Yen-Ling LIN ; Shih-Yuan CHEN ; Jen-Hau CHEN ; Ta-Fu CHEN ; Wei-J CHEN ; Yen-Ching CHEN ; Yi-Min CHU ; Yi-Ling HUANG ; Liang-Chuan LAI ; Li-Li WEN ; Shi-Yi YANG ; Ping-Keung YIP ; . YU SUN ; Department of Public Health. College of Public Health. National Taiwan University. Taipei. TWN ; Institute of Epidemiology and Preventive Medicine. College of Public Health. National Taiwan University. Taipei. TWN ; Research Center for Genes. Environment and Human Health. College of Public Health. National Taiwan University. Taipei. TWN |[BDSP. Notice produite par INIST-CNRS s9rR0xr9. Diffusion soumise à autorisation].Article
Andy LOCKETT ; Graeme CURRIE ; FINN (Rachael) : GBR. University of Sheffield. ; Graham Martin ; Justin WARING ; University of Warwick. Business School. Warwick Business School. Coventry. GBR |[BDSP. Notice produite par INIST-CNRS R0xmktCn. Diffusion soumise à autorisation]. We draw on institutional entrepreneurship theory to analyse the dynamics of institutional change in a healthcare context. The focus of our interest is in the rela[...]Article
Jirong Long ; William-J BLOT ; Todd EDWARDS ; . QIUYIN CAI ; Xiao-Ou SHU ; Lisa-B SIGNORELLO ; . WEI ZHENG ; Division of Epidemiology. Department of Medicine. School of Medicine. Vanderbilt University. Nashville. TN. USA |[BDSP. Notice produite par INIST-CNRS GoR0x989. Diffusion soumise à autorisation]. Type 2 diabetes (T2D) is up to twice as prevalent among African Americans as Caucasians. Recent genome-wide association studies (GWAS) have identified multiple co[...]Thèse
Cheikh Loucoubar , Diplôme : Thèse du réseau doctoral en santé publique animé par l'EHESP , 181p. , 2012Les études longitudinales sur une longue période permettent d’échantillonner plusieurs fois le phénomène étudié et ainsi, avec des mesures répétées, dégager une tendance confirmée. Mais, dès lors[...]
- Localisation : Rennes | Cote : THESE12/0003
Article
Steven-J LUBBE ; Peter BRODERICK ; CHANDLER (Ian) : GBR. Department of Histopathology. Royal Devon and Exeter Hospital. Exeter Devon. ; Maria-Chiara DI BERNARDO ; Richard-S HOULSTON ; Section of Cancer Genetics. Institute of Cancer Research. Sutton Surrey. GBR |[BDSP. Notice produite par INIST-CNRS oB998R0x. Diffusion soumise à autorisation]. To comprehensively evaluate the impact of recently identified colorectal cancer (CRC) variants at 1 q41,3q26.2,8q23.3,8q24.21,10p14,11q23.1,12q13.13,14q22.2,15q13[...]Article
Philip-J LUPO ; A.J. AGOPIAN ; Mark-A CANFIELD ; Claudia CHAPA ; Richard-H FINNELL ; . HUIPING ZHU ; D. KIM WALLER ; Laura-E MITCHELL ; Andrew-F OLSHAN ; Gary-M SHAW ; . WEI LU ; Dell Pediatric Research Institute. Department of Nutritional Sciences. University of Texas at Austin. Austin. TX. USA ; Human Genetics Center. Division of Epidemiology. Human Genetics and Environmental Sciences. School of Public Health. University of Texas. Houston. TX. USA |[BDSP. Notice produite par INIST-CNRS j7J9GR0x. Diffusion soumise à autorisation]. Few studies have evaluated genetic susceptibility related to diabetes and obesity as a risk factor for neural tube defects (NTDs). The authors investigated 23 sin[...]Article
Mitchell-J MACHIELA ; Demetrius ALBANES ; Naomi-E ALLEN ; Aurelio BARRICARTE ; H. BAS BUENO-DE-MESQUITA ; Sonja-I BERNDT ; Stephen CHANOCK ; Susan-M GAPSTUR ; Edward GIOVANNUCCI ; Christopher-A HAIMAN ; Brian-E HENDERSON ; David J. Hunter ; Eric-J JACOBS ; . JING MA ; Laurence-N KOLONEL ; Peter KRAFT ; Vittorio KROGH ; Loic LE MARCHAND ; Sara LINDSTROM ; J. MICHAEL GAZIANO ; Meir-J STAMPFER ; Victoria-L STEVENS ; Daniel-O STRAM ; Anne TJONNELAND ; Ruth TRAVIS ; Walter-C Willett |[BDSP. Notice produite par INIST-CNRS lp9t8R0x. Diffusion soumise à autorisation]. Observational studies have found an inverse association between type 2 diabetes (T2D) and prostate cancer (PCa), and genome-wide association studies have found co[...]Article
MIREA (Lucia) : CAN. Maternal-Infant Care Research Centre. Mount Sinai Hospital. Toronto. ON. ; BULL (Shelley-B) : CAN. Samuel Lunenfeld Research Institute. Mount Sinai Hospital. Toronto. ON. ; INFANTE-RIVARD (Claire) : CAN. Department of Epidemiology. Biostatistics and Occupational Health. Faculty of Medicine. McGill University. Montréal. PQ. ; LEI SUN (.) : CAN. Department of Statistics. Faculty of Arts and Science. University of Toronto. Toronto. ON. ; Division of Biostatistics. Dalla Lana School of Public Health. University of Toronto. Toronto. ON. CAN |[BDSP. Notice produite par INIST-CNRS l98CR0xA. Diffusion soumise à autorisation]. In genetic association studies, analyses integrating data or estimates from unrelated case-control individuals and case trios (case offspring and their parents) c[...]Article
Bhramar MUKHERJEE ; Jaeil AHN ; CHATTERJEE (Nilanjan) : USA. Division of Cancer Epidemiology and Genetics. National Cancer Institute. National Institutes of Health. Rockville. MD. ; GRUBER (Stephen-B) : USA. Department of Internal Medicine. Human Genetics. And Epidemiology. The University of Michigan. Ann Arbor. MI. ; Department of Biostatistics. School of Public Health. The University of Michigan. Ann Arbor. MI. USA |[BDSP. Notice produite par INIST-CNRS D8R0xFA7. Diffusion soumise à autorisation]. Several methods for screening gene-environment interaction have recently been proposed that address the issue of using gene-environment independence in a data-ada[...]Article
Kirsti MYKLESTAD ; Elisabeth-Balstad MAGNUSSEN ; Pal-Richard ROMUNDSTAD ; SALVESEN (Kjell-Asmund) : NOR. Institute of Laboratory Medicine. Women and Child Health. Norwegian University of Science and Technology. Trondheim. ; George-Davey Smith ; Lars-Johan VATTEN ; Department of Obstetrics. St Olavs Hospital. Trondheim University Hospital. St Olav. Trondheim. NOR |[BDSP. Notice produite par INIST-CNRS pR0xlIoG. Diffusion soumise à autorisation]. Low birth weight is associated with increased risk of cardiovascular disease and type 2 diabetes in later life. The fetal insulin hypothesis suggests that shared [...]Article
NAVON (Daniel) : USA. Department of Sociology. Columbia University. New York. NY. ; SHWED (Uri) : ISR. Department of Sociology and Anthropology. Ben Gurion University of the Negev. Beer Sheva. |[BDSP. Notice produite par INIST-CNRS 8R0x7q8n. Diffusion soumise à autorisation]. How can genetics reshape nosology ? This paper examines the way knowledge about a genetic mutation - the microdeletion at chromosomal locus 22q11.2 - transformed [...]Article
NON (Amy-L) : USA. Non is a Robert Wood Johnson Foundation Health and Society Scholar at Harvard University in Cambridge. Ma. ; Clarence-C GRAVLEE ; MULLIGAN (Connie-J) : USA. Genetics Institute. University of Florida. Gainesville. ; Department of Anthropology at the University of Florida. Gainesville. USA |[BDSP. Notice produite par INIST-CNRS InI9kR0x. Diffusion soumise à autorisation]. Objectives. We assessed the relative roles of education and genetic ancestry in predicting blood pressure (BP) within African Americans and explored the associati[...]Article
OROZCO (Gisela) : GBR. Arthritis Research Uk Epidemiology Unit. Manchester Academic Health Science Centre. The University of Manchester. ; IOANNIDIS (John-Pa) : USA. Stanford University Prevention Research Center. Stanford University School of Medicine. Stanford. CA. ; MORRIS (Andrew) : GBR. Wellcome Trust Centre for Human Genetics. University of Oxford. Oxford. ; ZEGGINI (Eleftheria) : GBR. Wellcome Trust Sanger Institute. Hinxton. |[BDSP. Notice produite par INIST-CNRS nR0x8C9G. Diffusion soumise à autorisation]. Background Genetic differences between men and women may contribute to sex differences in prevalence and progression of many common complex diseases. Using the WT[...]Article
Orestis-A PANAGIOTOU ; IOANNIDIS (John-Pa) : GRC. Biomedical Research Institute. Foundation for Research and Technology-Hellas. Ioannina. |[BDSP. Notice produite par INIST-CNRS nR0x9FIs. Diffusion soumise à autorisation]. Background Robust replication is a sine qua non for the rigorous documentation of proposed associations in the genome-wide association (GWA) setting. Currently, a[...]Article
Casey-M REBHOLZ ; Lydia-A BAZZANO ; Pierre BUEKENS ; Ji-Chun CHEN ; . DEPEI LIU ; . DONGFENG GU ; . DONGSHENG HU ; . FANGHONG LU ; Jian-Feng HUANG ; . JIANG HE ; . JIANJUN MU ; . JIANXIN LI ; . JIE CAO ; . JING CHEN ; . JIXIANG MA ; . XU JI ; Cardiovascular Institute and Fuwai Hospital. Chinese Academy of Medical Sciences and Peking Union Medical College. And National Center for Cardiovascular Disease. Beijing. CHN ; Department of Medicine. School of Medicine. Tulane University. New Orleans. LA. USA |[BDSP. Notice produite par INIST-CNRS nnnqR0xk. Diffusion soumise à autorisation]. Salt sensitivity of blood pressure (BP) is influenced by genetic and environmental factors. A dietary feeding study was conducted from October 2003 to July 2005 t[...]Article
Andrew-G RENEHAN ; Laura AUDI ; Gerhard BINDER ; Werner BLUM ; Pierre Bougnères ; Antonio CARRASCOSA ; Peter-E CLAYTON ; Anita HOKKEN-KOELEGA ; Alexander JORGE ; Reena MORJARIA ; Primus-E MULLIS ; Leena PATEL ; Christine-Dos SANTOS ; Mattea SOLOMON ; Maïté Tauber ; Andrew WHATMORE ; Marcel ZWAHLEN ; Centre for Biomedical Research on Rare Diseases. Instituto de Salud Carlos 3. Barcelona. ESP ; Department of Pediatric Endocrinology. Hopital Saint Vincent de Paul. Assistance Publique-Hôpitaux de Paris. Faculte de Medecine Paris Descartes. Paris. FRA ; Department of Pediatrics. Institut de Recerca. Hospital Vall d'Hebron and Autonomous University. Barcelona. ESP ; School of Biomedicine. University of Manchester. Manchester. GBR |[BDSP. Notice produite par INIST-CNRS nR0xoqD9. Diffusion soumise à autorisation]. Recombinant human growth hormone (rhGH) therapy is used in the long-term treatment of children with growth disorders, but there is considerable treatment response[...]Rapport
La médecine prédictive a pour objectif de déterminer chez chacun des sensibilités aux médicaments et des prédispositions biologiques à certaines maladies afin den retarder, voire den éviter, la[...]Article
The central ethical concern in public health remains the conflict between individual and group interests in controlling disease and promoting health. The balance point between utilitarian and libertarian visions of a well-ordered society shift o[...]Article
Reecha SOFAT ; Gonçalo ABECASIS ; Dominique-C BAAS ; Arthur-A BERGEN ; Shomi-S BHATTACHARYA ; Alan-C BIRD ; Kari-Eh BRANHAM ; Catey BUNCE ; Maria CAROLINA ORTUBE ; Juan-P Casas ; Usha CHAKRAVARTHY ; Li-L CHEN ; Valentina CIPRIANI ; Yvette-P CONLEY ; Angela-J CREE ; Paulus-Tv-m DE JONG ; Robert-E FERRELL ; Astrid FLETCHER ; Lars-G FRITSCHE ; Daniel GIBBS ; Michael-B GORIN ; Helen-L GRIFFITHS ; Aroon-D HINGORANI ; Johanna JAKOBSDOTTIR ; Sharon-A JENKINS ; . KANG ZHANG ; Claudia-N KEILHAUER ; Jane-C KHAN ; Caroline-Cw KLAVER ; Mark LATHROP ; Thierry LEVEILLARD ; Andrew LOTERY ; Samantha-S MANN ; Anthony-T MOORE ; Tune PETO ; Mati RAHU ; Johan-H SELAND ; Tiina SEPP ; Humma SHAHID ; Liam SMEETH ; Gisele SOUBRANE ; Anand SWAROOP ; Laura TOMAZZOLI ; Fotis TOPOUZIS ; Jesus VIOQUE ; Bernhard-Hf WEBER ; Andrew-R WEBSTER ; Daniel-E WEEKS ; John WHITTAKER ; John-Rw YATES ; Ian YOUNG ; . YUHONG CHEN ; Sepideh ZAREPARSI |[BDSP. Notice produite par INIST-CNRS R0x9H8m9. Diffusion soumise à autorisation]. Background Variation in the complement factor H gene (CFH) is associated with risk of late age-related macular degeneration (AMD). Previous studies have been case[...]Article
Eleonora STAINES-URIAS ; Juan-P Casas ; Pat DOYLE ; Frank DUDBRIDGE ; Aroon-D HINGORANI ; IOANNIDIS (John-Pa) : GRC. Department of Hygiene and Epidemiology. University of Ioannina School of Medicine. Ioannina. ; KEATING (Brendan-J) : USA. The Institute for Translational Medicine and Therapeutics. School of Medicine. University of Pennsylvania. Philadelphia. PA. ; Maria-C PAEZ ; Norma-C SERRANO ; Centro de Investigaciones Biomedicas. Facultad de Ciencias de la Salud. Universidad Autonoma de Bucaramanga. COL ; Faculty of Epidemiology and Population Health. London School of Hygiene & Tropical Medicine. GBR ; Faculty of Population Health Science. University College London. GBR |[BDSP. Notice produite par INIST-CNRS I97tR0xp. Diffusion soumise à autorisation]. Background Pre-eclampsia is thought to have a polygenic basis, but the identification of susceptibility genes and the quantification of associated risks have been[...]