Titre : | Pregnant and stressed: The impact of maternal prenatal depression and anxiety symptomatology on child emotional and behavioural development trajectories in the EDEN cohort |
Auteurs : | Kadri-Ann Kallass ; Ecole des hautes études en santé publique (EHESP) (Rennes, FRA) |
Type de document : | Mémoire |
Année de publication : | 2022 |
Description : | 51p. |
Langues: | Anglais |
Classement : | MPH22/ (Master EHESP International master of public health - MPH) |
Mots-clés : | Foetus ; Stress ; Grossesse ; Impact ; Dépression postpartum ; Enfant ; Etat santé ; France ; Trouble affectivité ; Trouble anxieux |
Résumé : |
Introduction: In utero exposure to prenatal maternal stress as measured through depression and anxiety symptomatology has been associated with adverse emotional and behavioural characteristics up to middle childhood. This study aimed to quantify and characterize the associations in a French sample.
Methods: 1135 children from the EDEN mother–child cohort set up in France were followed from pregnancy to the age of 11 years. Group-based trajectory modelling was used to model trajectories of behavioural and emotional characteristics measured at 4 timepoints via a parent-administered Strengths and Difficulties Questionnaire. Using propensity scores and inverse probability weighting to account for confounding factors, multinomial logistic regressions were used to quantify the associations. Stratified analyses were conducted by sex and reporting psychiatrist visits (1) during pregnancy and (2) from birth to 8 years after. Results: Compared with children who were not exposed to high levels of maternal depressive symptoms in utero, those who did had a higher likelihood of presenting with high levels of emotional symptoms (ORIPW = 1.90, 95% CI 1.21-2.99), conduct problems (ORIPW = 1.68, 95% CI 1.06-2.64), inattention-hyperactivity (ORIPW = 1.66, 95% CI 1.06-2.61) and peer relationship problems (ORIPW = 1.90, 95% CI 1.06-3.34). Prenatal maternal anxiety was significantly associated with high levels of emotional symptoms (ORIPW = 1.96, 95% CI 1.21-3.16) and low levels of prosocial behaviours (ORIPW = 1.82, 95% CI 1.00-3.30). Females exposed to prenatal depression (ORIPW = 1.89, 95% CI 1.00-3.58) and anxiety (ORIPW = 2.41, 95% CI 1.26-4.63) were more likely to follow a high trajectory of emotional symptoms. Males exposed to prenatal depression (ORIPW = 2.11, 95% CI 1.09-4.10) and anxiety (ORIPW = 2.23, 95% CI 1.03-4.70) were more likely to be classified in the persistently high symptoms trajectory of conduct problems. Males exposed to prenatal maternal depression were additionally more likely to follow a high symptom trajectory of inattention-hyperactivity (ORIPW = 1.88, 95% CI 1.00-3.53) and low symptom trajectory of prosocial behaviours (ORIPW = 2.08, 95% CI 1.05-4.13). No increased risks by prenatal depression and anxiety exposure were identified in children of mothers who reported visiting a psychiatrist either during or up to 8 years after the pregnancy. Conclusion: Prenatal maternal depression and anxiety are associated with increased risks of adverse emotion-behavioural outcomes in children. The associations with specific outcomes differ by sex and are buffered by accessing psychiatric care both during and after pregnancy. The study provides further evidence that failure to address mental health during pregnancy would be a missed opportunity to intervene and support children and families. |
Diplôme : | Master MPH of public health |
Plan de classement simplifié : | Master of Public Health - master international de Santé Public (MPH) |
En ligne : | https://documentation.ehesp.fr/memoires/2022/mph/kadri_ann_kallas.pdf |
Exemplaires (1)
Code-barres | Cote | Support | Localisation | Section | Disponibilité |
---|---|---|---|---|---|
096497 | MPH22/0007 | Mémoire | Rennes | Salle des Glénan | Empruntable Disponible |