Titre :
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Inverse Association of Plasma Vanadium Levels With Newly Diagnosed Type 2 Diabetes in a Chinese Population (2014)
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Auteurs :
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. XIA WANG ;
Department of Nutrition and Food Hygiene and Ministry of Education Key Laboratory of Environment and Health. School of Public Health. Tongji Medical College, Huazhong University of Science and Technology (Wuhan, Chine) ;
. TAOPING SUN ;
. JUN LIU ;
. ZHILEI SHAN ;
. YILIN JIN ;
. SIJING CHEN ;
. WEI BAO ;
Frank-B HU ;
. LIEGANG LIU
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Type de document :
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Article
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Dans :
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American journal of epidemiology (vol. 180, n° 4, août 2014)
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Pagination :
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378-384
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Langues:
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Anglais
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Mots-clés :
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Association
;
Plasma sanguin
;
Homme
;
Chine
;
Epidémiologie
;
Asie
;
Glande endocrine [pathologie]
;
Oligoélément
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Résumé :
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[BDSP. Notice produite par INIST-CNRS R0xJq9AA. Diffusion soumise à autorisation]. Vanadium compounds have been proposed to have beneficial effects on the pathogenesis and complications of type 2 diabetes. Our objective was to evaluate the association between plasma vanadium levels and type 2 diabetes. We performed a case-control study involving 1,598 Chinese subjects with or without newly diagnosed type 2 diabetes (December 2004-December 2007). Cases and controls were frequency-matched by age and sex. Plasma vanadium concentrations were measured and compared between groups. Analyses showed that plasma vanadium concentrations were significantly lower in cases with newly diagnosed type 2 diabetes than in controls (P=0.001). Mean plasma vanadium levels in participants with and without diabetes were 1.0 mug/L and 1.2 mug/L, respectively. Participants in the highest quartile of plasma vanadium concentration had a notably lower risk of newly diagnosed type 2 diabetes (odds ratio=0.26,95% confidence interval : 0.19,0.35 ; P
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