Titre : | Obesity and Mortality After Breast Cancer by Race/Ethnicity : The California Breast Cancer Survivorship Consortium (2014) |
Auteurs : | Marilyn-L KWAN ; Esther-M JOHN ; Division of Research, Kaiser Permanente Northern California (Oakland CA, Etats-Unis) ; Bette-J CAAN ; Cancer Prevention Institute of California (Fremont CA, Etats-Unis) ; Division of Epidemiology, Stanford University School of Medicine (Stanford CA, Etats-Unis) ; Valerie-S LEE ; Leslie BERNSTEIN ; Stanford Cancer Institute, Stanford University School of Medicine (Stanford CA, Etats-Unis) ; Division of Cancer Etiology. Department of Population Sciences. Beckman Research Institute, City of Hope (Duarte CA, Etats-Unis) ; Iona CHENG ; Department of Preventive Medicine, University of Southern California (Los Angeles CA, Etats-Unis) ; Scarlett-Lin GOMEZ ; Brian-E HENDERSON ; Norris Comprehensive Cancer Center, University of Southern California (Los Angeles CA, Etats-Unis) ; Theresa-Hm KEEGAN ; Allison-W KURIAN ; . YANI LU ; Kristine-R MONROE ; Janise-M ROH ; Salma SHARIFF-MARCO ; Richard SPOSTO ; Cheryl VIGEN ; Anna-H WU |
Type de document : | Article |
Dans : | American journal of epidemiology (vol. 179, n° 1, janvier 2014) |
Pagination : | 95-111 |
Langues: | Anglais |
Mots-clés : | Obésité ; Epidémiologie ; Mortalité ; Sein ; Race ; Ethnie ; Tissu adipeux ; Survie ; Amérique ; Cancer ; Anthropométrie ; Amérique du Nord |
Résumé : | [BDSP. Notice produite par INIST-CNRS R0x8CCkp. Diffusion soumise à autorisation]. We investigated body size and survival by race/ethnicity in 11,351 breast cancer patients diagnosed from 1993 to 2007 with follow-up through 2009 by using data from questionnaires and the California Cancer Registry. We calculated hazard ratios and 95% confidence intervals from multivariable Cox proportional hazard model-estimated associations of body size (body mass index (BMI) (weight (kg)/height (m) 2) and waist-hip ratio (WHR)) with breast cancer-specific and all-cause mortality. Among 2,744 ascertained deaths, 1,445 were related to breast cancer. Being underweight (BMI=40) was suggestive of increased risk (HR=1.43,95% CI : 0.84,2.43). In Latinas, only the morbidly obese were at high risk of death (HR=2.26,95% CI : 1.23,4.15). No BMI-mortality associations were apparent in African Americans and Asian Americans. High WHR (quartile 4 vs. quartile 1) was associated with breast cancer mortality in Asian Americans (HR=2.21,95% CI : 1.21,4.03 ; P for trend=0.01), whereas no associations were found in African Americans, Latinas, or non-Latina whites. For all-cause mortality, even stronger BMI and WHR associations were observed. The impact of obesity and body fat distribution on breast cancer patients'risk of death may vary across racial/ethnic groups. |
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Code-barres | Cote | Support | Localisation | Section | Disponibilité |
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9782021120554 | AME | Périodique | Rennes | Magasin | Empruntable Disponible |