Résumé :
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[BDSP. Notice produite par INIST-CNRS A9R0x8DC. Diffusion soumise à autorisation]. Background The relationship between alcohol intake and the risk for gastric cancer is not fully understood. The association between alcohol consumption and the risk for gastric cancer was investigated in the Korean population with the ALDH2 genotype. Methods From 2003 to 2008,445 patients with gastric cancer and 370 control subjects>=50 years of age were included in the analysis. Logistic regression models including age, gender, education, smoking and drinking status, Helicobacter pylori infection and ALDH2 genotype were evaluated to estimate the adjusted odds ratios (ORs) for the development of gastric cancer. Results For all subjects, the risk for gastric cancer was increased in ex-drinkers [OR 1.68,95% confidence interval (CI) 1.07-2.64], but not in current drinkers. Subjects with inactive ALDH2 *2 allele (s) showed a lower level of alcohol consumption than ALDH2 *l/*l homozygotes (P
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