Titre :
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GEIRA : gene-environment and gene-gene interaction research application. (2011)
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Auteurs :
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. BO DING ;
Lars ALFREDSSON ;
Henrik KALLBERG ;
Lars KLARESKOG ;
Leonid PADYUKOV ;
Rheumatology Unit. Department of Medicine. Karolinska Institutet. Stockholm. SWE
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Type de document :
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Article
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Dans :
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European journal of epidemiology (vol. 26, n° 7, 2011)
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Pagination :
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557-561
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Langues:
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Anglais
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Mots-clés :
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Santé environnementale
;
Gène
;
Génétique
;
Programme
;
Homme
;
Epidémiologie
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Résumé :
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[BDSP. Notice produite par INIST-CNRS ss998R0x. Diffusion soumise à autorisation]. The GEIRA (Gene-Environment and Gene-Gene Interaction Research Application) algorithm and subsequent program is dedicated to genome-wide gene-environment and gene-gene interaction analysis. It implements concepts of both additive and multiplicative interaction as well as calculations based on dominant, recessive and co-dominant genetic models, respectively. Estimates of interactions are incorporated in a single table to make the output easily read. The algorithm is coded in both SAS and R. GEIRA is freely available to non-commercial users. Additional information, including user's manual and example datasets is available online at http :/www. epinet. se.
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