Résumé :
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[BDSP. Notice produite par INIST-CNRS kt8AR0xs. Diffusion soumise à autorisation]. Among men of European ancestry, diabetics have a lower risk of prostate cancer than do nondiabetics. The biologic basis of this association is unknown. The authors have examined whether the association is robust across populations in a population-based prospective study. The analysis included 5,941 prostate cancer cases identified over a 12-year period (1993-2005) among 86,303 European-American, African-American, Latino, Japanese-American, and Native Hawaiian men from the Multiethnic Cohort. The association between diabetes and prostate-specific antigen (PSA) levels (n=2,874) and PSA screening frequencies (n=46,970) was also examined. Diabetics had significantly lower risk of prostate cancer than did nondiabetics (relative risk=0.81,95% confidence interval (Cl) : 0.74,0.87 ; P
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