Titre :
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Sibship size, Helicobacter pylori infection and chronic atrophic gastritis : a population-based study among 9444 older adults from Germany. (2010)
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Auteurs :
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. LEI GAO ;
Hermann BRENNER ;
Elke RAUM ;
Dietrich ROTHENBACHER ;
STEGMAIER (Christa) : DEU. Epidemiological Cancer Registry of Saarland. Saarbrücken. ;
Melanie-N WECK
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Type de document :
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Article
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Dans :
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International journal of epidemiology (vol. 39, n° 1, 2010)
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Pagination :
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129-134
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Langues:
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Anglais
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Mots-clés :
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Bactériose
;
Helicobacter pylori
;
Personne âgée
;
Allemagne
;
Infection
;
Bactérie
;
Homme
;
Europe
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Résumé :
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[BDSP. Notice produite par INIST-CNRS mR0x9EH8. Diffusion soumise à autorisation]. Background Early-life social environment has been suggested to play an important role during the development of Helicobacter pylori-related gastric diseases. We aimed to assess the association of sibship size with H. pylori infection and chronic atrophic gastritis (CAG) in a population-based study from Germany. Methods In the baseline examination of ESTHER, a study conducted in Saarland, serological measurements of pepsinogen I and II and H. pylori antibodies were taken in 9444 participants aged 50-74 years. Information on potential risk factors and medical history were obtained by self-administered standardized questionnaire. Results A strong dose-response relationship between sibship size and H. pylori seroprevalence was observed (P
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