Résumé :
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[BDSP. Notice produite par INIST-CNRS wuR0xopx. Diffusion soumise à autorisation]. Objectives. We examined the association between physical activity and cognitive functioning in middle age. Methods. Data were derived from a prospective occupational cohort study of 10308 civil servants aged 35-55 years at baseline (phase 1 ; 1985-1988). Physical activity level. categorized as low, medium, or high, was assessed at phases 1,3 (1991-1994), and 5 (1997-1999). Cognitive functioning was tested at phase 5, when respondents were 46-68 years old. Results. In both prospective (odds ratio [OR]=1.65 ; 95% confidence interval [CI]=1.30,2.10) and cross-sectional (OR=1.79 ; 95% CI=1.38,2.32) analyses, low levels of physical activity were a risk factor for poor performance on a measure of fluid intelligence. Analyses aimed at assessing cumulative effects (summary of physical activity levels at the 3 time points) showed a graded linear relationship with fluid intelligence, with persistently low levels of physical activity being particularly harmful (OR=2.21 ; 95% CI=1.37. 3.57). Conclusions. Low levels of physical activity are a risk factor for cognitive functioning in middle age, fluid intelligence in particular.
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