Titre : | Blood Cadmium and Lead and Chronic Kidney Disease in US Adults : A Joint Analysis. (2009) |
Auteurs : | Ana NAVAS-ACIEN ; Eliseo GUALLAR ; Bernard JAAR ; MUNTNER (Paul) : USA. Department of Community and Preventive Medicine. Mount Sinai School of Medicine. New York. NY. ; Ellen SILBERGELD ; Maria TELLEZ-PLAZA ; Virginia WEAVER ; Department of Cardiovascular Epidemiology and Population Genetics. Centro Nacional de Investigaciones Cardiovasculares. Madrid. ESP ; Welch Center for Prevention. Epidemiology. And Clinical Research. Johns Hopkins Medical Institutions. Baltimore. MD. USA |
Type de document : | Article |
Dans : | American journal of epidemiology (vol. 170, n° 9, 2009) |
Pagination : | 1156-1164 |
Langues: | Anglais |
Mots-clés : | Sang ; Cadmium ; Adulte ; Albumine ; Urine ; Créatinine ; Taux ; Epidémiologie ; Amérique ; Homme ; Insuffisance rénale ; Glande endocrine [pathologie] ; Diabète ; Maladie associée ; Amérique du Nord |
Résumé : | [BDSP. Notice produite par INIST-CNRS ooBFR0xk. Diffusion soumise à autorisation]. Environmental cadmium and lead exposures are widespread, and both metals are nephrotoxic at high exposure levels. Few studies have evaluated the associations between low-level cadmium and clinical renal outcomes, particularly with respect to joint cadmium and lead exposure. The geometric mean levels of blood cadmium and lead were 0.41 mug/L (3.65 nmol/L) and 1.58 mug/dL (0.076 mumol/L), respectively, in 14,778 adults aged>20 years who participated in the National Health and Nutrition Examination Survey (1999-2006). After adjustment for survey year, sociodemographic factors, chronic kidney disease risk factors, and blood lead, the odds ratios for albuminuria (>30 mg/g creatinine), reduced estimated glomerular filtration rate (eGFR) ( |