Résumé :
|
[BDSP. Notice produite par INIST-CNRS R0xzQHRe. Diffusion soumise à autorisation]. Objective : We examined a two-step case-finding strategy where the Cummings'risk score (NEJM 1995) was applied in a population-based setting together with bone mineral density (BMD) measurements in order to validate its ability to identify women with high risk of hip fracture. Methods : All Tromso women aged between 65 and 74 were invited to the Tromso Osteoporosis Study (TROST) together with a 5% random sample of women aged 75-84 years (n=1410). All had forearm BMD measurements in 1994/95 and were followed for 5 years with respect to first hip fracture. A risk score was constructed matching the Cummings score as closely as possible. Results : In all 759,578 and 73 women had 0-2,3-4 and 5+risk factors, respectively. Women with 5+risk factors had a 5-year hip fracture risk of 11% (95% confidence interval (CI) 3.7-18.2%). BMD screening applied to these women identified 74% of them as osteoporotic and 19% as osteopenic with, respectively, 5-year hip fracture risk of 13% and 7.1%. Conclusion : In a population different from the one the score was generated in, this simple risk score identifies a group of women with high risk of hip fractures. With no additional BMD measurements, those high-risk women could benefit from early intervention measures.
|