Résumé :
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[BDSP. Notice produite par INIST-CNRS 9UFR0xk5. Diffusion soumise à autorisation]. Some evidence suggests that smoking, a family history of hematopoietic cancer, and use of hair dyes are associated with t (14 ; 18) - defined subsets of non-Hodgkin's lymphoma (NHL) in men. To further evaluate these associations and to expand them to women, the authors determined t (14 ; 18) (q32 ; q21) status by fluorescence in situ hybridization in 172 of 175 tumor blocks from a population-based case-control study conducted in Nebraska during 1983-1986. Exposures in 65 t (14 ; 18) - positive cases and 107 t (14 ; 18) - negative cases were compared with those among 1,432 controls. Odds ratios and 95% confidence intervals were calculated using polytomous logistic regression. Among men, smoking was not associated with risk of t (14 ; 18) - positive or - negative NHL. Among women who had ever smoked cigarettes, there was an association with risk of t (14 ; 18) - negative NHL (odds ratio (OR)=1.9,95% confidence interval (Cl) : 1.1,3.3) but nott (14 ; 18) - positive NHL (p-difference=0.01). The risks for t (14 ; 18) - negative NHL among women increased with longer duration (>30 years : OR=2.1,95% Cl : 1.1,4.1) and early initiation (age
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