Titre :
|
Seroprevalence of varicella antibodies among pregnant women in Lyon-France. (2007)
|
Auteurs :
|
M. SAADATIAN-ELAHI ;
E. CAULIN ;
C. DEL SIGNORE ;
T. DERROUGH ;
B. LINA ;
Y. MEKKI ;
THIERRY (J.) : FRA. Laboratoire Charcot. Le Point du Jour. Lyon. ;
P. VANHEMS ;
Cnrs. Lyon. FRA ;
Hospices civils de Lyon. Département d'Hygiène Epidémiologie et Prévention. Lyon. FRA ;
Université Claude Bernard. Laboratoire de Virologie. Lyon. FRA ;
Université de Lyon. Laboratoire d'Epidémiologie et de Santé Publique. Lyon. FRA
|
Type de document :
|
Article
|
Dans :
|
European journal of epidemiology (vol. 22, n° 6, 2007)
|
Pagination :
|
405-409
|
Langues:
|
Anglais
|
Mots-clés :
|
Sérologie
;
Prévalence
;
Epidémiologie
;
Varicelle
;
Anticorps
;
Grossesse
;
Femme
;
Homme
;
Femme enceinte
;
Adulte
;
France
;
Rhône Alpes
;
Virose
;
Infection
;
Europe
;
Virus
|
Résumé :
|
[BDSP. Notice produite par INIST-CNRS pX8R0xc1. Diffusion soumise à autorisation]. The purpose of the study was to calculate the seroprevalence of immunity to the varicella-zoster virus (VZV) infection and to evaluate the positive predictive value (PPV) and the negative predictive value (NPV) of the self-reported history of VZV infection in pregnant women. A cross sectional study was conducted in 18 private medical analysis laboratories. Information on socio-demographic characteristics and past history of varicella or zoster were collected using a questionnaire. Blood samples were obtained to determine the serological levels of past exposure to VZV. Overall, 486 pregnant women were recruited. The seroprevalence of VZV antibodies was 98.8%. Six women were seronegative, of whom four were primiparous. The PPV was high (99.5%) while the NPV was only 10.3%. The PPV is a reliable marker of prior VZV infection. In contrast, a negative history does not predict lack of immunity and should be completed by serological analysis which might be introduced to routine antenatal blood tests.
|