Résumé :
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[BDSP. Notice produite par INIST-CNRS eR0xyDTF. Diffusion soumise à autorisation]. Occupational factors contribute to a significant fraction of respiratory disease and symptoms. The authors evaluated the role of occupational exposures in asthma, chronic bronchitis, and respiratory symptoms in the Singapore Chinese Health Study, a population-based cohort of adults aged 45-74 years at enrollment in 1993-1998. Information on occupations and occupational exposures was collected at enrollment for 52,325 subjects for whom respiratory outcomes were obtained via follow-up interviews in 1999-2004. Exposure to dusts from cotton, wood, metal, minerals, and/or asbestos was associated with nonchronic cough and/or phlegm (odds ratio (OR)=1.19,95% confidence interval (Cl) : 1.08,1.30), chronic bronchitis (OR=1.26,95% Cl : 1.01,1.57), and adult-onset asthma (OR=1.14,95% Cl : 1.00,1.30). Cotton dust was the major contributor to respiratory symptoms. Vapor exposure from chemical solvents, dyes, cooling oils, paints, wood preservatives, and/or pesticides was associated with nonchronic cough or phlegm (OR=1.14,95% Cl : 1.03,1.27), chronic dry cough (OR=1.55,95% Cl : 1.19,2.01), and adult-onset asthma (OR=1.34,95% Cl : 1.15,1.56). Chemical solvents, cooling oils, and pesticides were the major contributors to respiratory symptoms. These data support the role of occupational exposures in the etiology of respiratory illness in a population-based cohort in Singapore with a low prevalence of atopic illness.
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