Titre :
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Childhood acute lymphoblastic leukemia and infections in the first year of life : A report from the United Kingdom childhood cancer study. (2007)
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Auteurs :
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E. ROMAN ;
P. ANSELL ;
J.M. BIRCH ;
T. EDEN ;
M. GREAVES ;
S. KINSEY ;
P.A. MCKINNEY ;
C.D. MITCHELL ;
J. SIMPSON
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Type de document :
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Article
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Dans :
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American journal of epidemiology (vol. 165, n° 5, 2007)
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Pagination :
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496-504
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Langues:
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Anglais
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Mots-clés :
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Infection
;
Cancer
;
Royaume Uni
;
Europe
;
Epidémiologie
;
Nourrisson
;
Homme
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Résumé :
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[BDSP. Notice produite par INIST-CNRS KFBR0xEL. Diffusion soumise à autorisation]. The United Kingdom Childhood Cancer Study was designed to examine the relation between childhood cancer and preceding exposure to infectious diseases. The authors analyzed the relation between diagnosis (1991-1996) of acute lymphoblastic leukemia (ALL) at ages 2-5 years and clinically diagnosed infections in infancy. Almost all study children (96% of both cases and controls) were taken to a general practitioner for a non-immunization-associated visit at least once before their first birthday. Children diagnosed with ALL had significantly more clinically diagnosed infectious episodes in infancy than did controls ; the average number of episodes was 3.6 (95% confidence interval (Cl) : 3.3,3.9) versus 3.1 (95% Cl : 2.9,3.2). This case-control difference was most apparent in the neonatal period (
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