Titre : | A strong secular trend in serum gamma-glutamyltransferase from 1996 to 2003 among South Korean men. (2006) |
Auteurs : | Duk-Hee LEE ; Yongchool BOO ; Byungyeol CHUN ; Myung-Hwa HA ; David-Rjr JACOBS ; Sin KAM ; Jangkyu LEE ; Kyungeun SONG ; Lyn Steffen ; Health Promotion Research Center. Daegu. KOR ; Kyungpook National University. School of Medicine. Department of Preventive Medicine. Daegu. KOR |
Type de document : | Article |
Dans : | American journal of epidemiology (vol. 163, n° 1, Janvier 2006) |
Pagination : | 57-65 |
Langues: | Anglais |
Mots-clés : | Hypercholestérolémie ; Tendance séculaire ; Sérum ; Enzyme ; Corée ; Asie ; Homme ; Vieillissement ; Alanine aminotransférase ; Aminotransférase ; Cholestérol ; Epidémiologie ; Lipoprotéine ; Lipide ; Métabolisme [pathologie] ; Hyperlipoprotéinémie ; Corée du Sud |
Résumé : | [BDSP. Notice produite par INIST-CNRS DvR0xOsD. Diffusion soumise à autorisation]. Serum gamma-glutamyltransferase (GGT) concentration, within its normal range, has recently been proposed as a reliable marker of oxidative stress. Oxidative stress plays a central pathogenic role in many metabolic and/or cardiovascular diseases, incidences of which have recently increased in South Korea. Since serum GGT has strong associations with these diseases and their risk factors, the authors hypothesized a corresponding secular trend of increasing serum GGT levels in South Korea. Study subjects were 8,072 male workers at a large steel company who were aged 24-44 years at baseline and had received annual physical examinations from 1996 to 2003. The secular trend was a 0.1066-units/liter increase in In (GGT) level per calendar year (a 180% increase during the 7-year follow-up period) (p |
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