Résumé :
|
[BDSP. Notice produite par INIST-CNRS koR0x8C9. Diffusion soumise à autorisation]. Hormone replacement therapy (HRT) may reduce lung cancer risk. Dietary boron may have actions similar to those of HRT ; however, no previous study has reported the associations between dietary boron intake and lung cancer risk or the joint effects of boron intake and HRT use on lung cancer risk. The authors examined the associations between boron intake and the joint effects of boron intake and HRT on lung cancer risk in women. In an ongoing case-control study in Houston, Texas (July 1995 through April 2005, end date for this analysis), 763 women were diagnosed with lung cancer, and 838 were matched healthy controls with data on both diet and HRT. Multiple logistic regression analyses were conducted to assess the associations between dietary boron and HRT with lung cancer risk. After adjustment for potential confounders, the odds ratios for lung cancer with decreasing quartiles of dietary boron intake were 1.0,1.39 (95% confidence interval (Cl) : 1.02,1.90), 1.64 (95% Cl : 1.20,2.24), and 1.95 (95% Cl : 1.42,2.68) mg/day, respectively, for all women (rhôrend
|