Résumé :
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[BDSP. Notice produite par INIST-CNRS AR0x8q7r. Diffusion soumise à autorisation]. The relation between parental history of hypertension and blood pressure response to potassium intake is unknown. A 7-day high-sodium followed by a 7-day high-sodium plus potassium dietary-feeding study was conducted from 2003 to 2005 among 1,871 Chinese participants. Those with a maternal history of hypertension had larger systolic blood pressure responses to potassium compared with those without : - 4.31 (95% confidence interval (CI) : - 4.99, - 3.62) mm Hg versus - 3.35 (95% CI : - 4.00, - 2.70) mm Hg, respectively (Pdifference=0.002). A consistent trend was observed for diastolic blood pressure responses : - 1.80 (95% CI : - 2.41, - 1.20) mm Hg versus - 1.35 (95% CI : - 1.95, - 0.74) mm Hg, respectively (P=0.07). Stronger associations between early onset maternal hypertension and blood pressure responses were noted, with systolic blood pressure decreases of - 4.80 (95% CI : - 5.65, - 3.95) mm Hg versus - 3.55 (95% CI : - 4.17, - 2.93) mm Hg and diastolic blood pressure decreases of - 2.25 (95% CI : - 3.01, - 1.50) mm Hg versus - 1.42 (95% CI : - 1.99, - 0.85) mm Hg among those with early onset maternal hypertension versus those without, respectively (P=0.001 and 0.009, respectively). Odds ratios for high potassium sensitivity were 1.36 (95% CI : 0.96,1.92) and 1.60 (95% CI : 1.08,2.36) for those with maternal hypertension and early onset maternal hypertension, respectively (P=0.08 and 0.02, respectively). Potassium supplementation could help to reduce blood pressure among those with a maternal history of hypertension.
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