Titre : | Environmental Exposures and Invasive Meningococcal Disease : An Evaluation of Effects on Varying Time Scales. (2009) |
Auteurs : | KINLIN (Laura-M) : CAN. Dalla Lana School of Public Health. University of Toronto. Toronto. ON. ; David-N FISMAN ; JOHNSON (Caroline-C) : USA. Philadelphia Department of Public Health. Philadelphia. PA. ; NG (Victoria) : AUS. Australian National University. Canberra New South Wales. ; Cvictor SPAIN ; Alexander-Nj White ; Faculty of Medicine. University of Toronto. Toronto. ON. CAN ; Ontario Agency for Health Protection and Promotion. Toronto. ON. CAN ; Research Institute of the Hospital for Sick Children. Toronto. ON. CAN |
Type de document : | Article |
Dans : | American journal of epidemiology (vol. 169, n° 5, 2009) |
Pagination : | 588-595 |
Langues: | Anglais |
Mots-clés : | Méningite ; Santé environnementale ; Environnement ; Evaluation ; Enquête cas témoin ; Epidémiologie ; Bactérie ; Méningocoque ; Homme ; Bactériose ; Infection |
Résumé : | [BDSP. Notice produite par INIST-CNRS oR0x98rJ. Diffusion soumise à autorisation]. Invasive meningococcal disease (IMD) is an important cause of meningitis and bacteremia worldwide. Seasonal variation in IMD incidence has long been recognized, but mechanisms responsible for this phenomenon remain poorly understood. The authors sought to evaluate the effect of environmental factors on IMD risk in Philadelphia, Pennsylvania, a major urban center. Associations between monthly weather patterns and IMD incidence were evaluated using multivariable Poisson regression models controlling for seasonal oscillation. Short-term weather effects were identified using a case-crossover approach. Both study designs control for seasonal factors that might otherwise confound the relation between environment and IMD. Incidence displayed significant wintertime seasonality (for oscillation, P |