Titre :
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Estimation of the Relative Excess Risk Due to Interaction and Associated Confidence Bounds. (2009)
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Auteurs :
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David-B RICHARDSON ;
Jay-S KAUFMAN
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Type de document :
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Article
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Dans :
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American journal of epidemiology (vol. 169, n° 6, 2009)
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Pagination :
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756-760
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Langues:
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Anglais
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Mots-clés :
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Estimation
;
Intervalle confiance
;
Facteur risque
;
Epidémiologie
;
Homme
;
Risque relatif
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Résumé :
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[BDSP. Notice produite par INIST-CNRS tsIpR0xk. Diffusion soumise à autorisation]. The relative excess risk due to interaction (RERI) provides a useful metric of departure from additivity of effects on a relative risk scale. In this paper, the authors show that RERI is identical to the product term in a linear odds ratio or a linear relative risk model. SAS and STATA codes are provided for fitting a linear odds ratio model that directly parameterizes RERI. In addition, this paper presents a method for obtaining likelihood-based 95% confidence bound estimates for RERI. The authors show that likelihood-based confidence intervals may differ substantially from the asymptotic confidence interval estimates advocated by previous authors. The approach presented in this paper should facilitate estimation of RERI and associated likelihood-based confidence bounds, by using standard statistical packages.
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