Titre : | Paternal age and epilepsy in the offspring. (2005) |
Auteurs : | Mogens VESTERGAARD ; Kreesten-M MADSEN ; MORK (Alissa) : USA. Division of Environmental and Occupational Health. University of Minnesota School of Public Health. Minneapolis. MN. ; OLSEN (Jorn) : USA. Department of Epidemiology. Ucla School of Public Health. Los Angeles. CA. ; University of Aarhus. Department of Epidemiology. Institute of Public Health. Danish Epidemiology Science Centre. Aarhus. DNK |
Type de document : | Article |
Dans : | European journal of epidemiology (vol. 20, n° 12, 2005) |
Pagination : | 1003-1005 |
Langues: | Anglais |
Mots-clés : | Epilepsie ; Famille descendante ; Epidémiologie ; Homme ; Système nerveux [pathologie] |
Résumé : | [BDSP. Notice produite par INIST-CNRS DER0xPqx. Diffusion soumise à autorisation]. Advanced paternal age is associated with a higher rate of de novo mutation in sperm cells and mental disorders in the offspring. In a population based cohort study of 96,654 children, we found that fathers aged 35 years or more were slightly more likely to have a child diagnosed with epilepsy compared to fathers aged 25-29 years. Our data suggest a modest paternal effect on the aetiology of epilepsy. |