Titre : | Menopause-associated Symptoms and Cognitive Performance : Results From the Study of Women's Health Across the Nation. (2010) |
Auteurs : | Gail-A GREENDALE ; AVIS (Nancy) : USA. Department of Public Health Sciences. School of Medicine. University of California. Davis. CA. ; GOLD (Ellen-B) : USA. Perinatal and Reproductive Psychiatry. Massachusetts General Hospital. Harvard Medical School. Boston. MA. ; Mei-Hua HUANG ; JOFFE (Hadine) : USA. Department of Epidemiology. Graduate School of Public Health. University of Pittsburgh. Pittsburgh. PA. ; Arun-S KARLAMANGLA ; Teresa SEEMAN ; Marike VUGE ; Richard-G WIGHT ; Department of Social Sciences and Health Policy. Wake Forest University School of Medicine. Winston Salem. NC. USA ; Division of Geriatrics. David Geffen School of Medicine. University of California. Los Angeles. CA. USA |
Type de document : | Article |
Dans : | American journal of epidemiology (vol. 171, n° 11, 2010) |
Pagination : | 1214-1224 |
Langues: | Anglais |
Mots-clés : | Ménopause ; Homme ; Femme ; Symptôme ; Fonction cognitive ; Performance ; Résultat ; Mémoire ; Epidémiologie |
Résumé : | [BDSP. Notice produite par INIST-CNRS A8HR0xGn. Diffusion soumise à autorisation]. A long-standing, but unproven hypothesis is that menopause symptoms cause cognitive difficulties during the menopause transition. This 6-year longitudinal cohort study of 1,903 midlife US women (2000-2006) asked whether symptoms negatively affect cognitive performance during the menopause transition and whether they are responsible for the negative effect of perimenopause on cognitive processing speed. Major exposures were depressive, anxiety, sleep disturbance, and vasomotor symptoms and menopause transition stages. Outcomes were longitudinal performance in 3 domains : processing speed (Symbol Digit Modalities Test (SDMT)), verbal memory (East Boston Memory Test), and working memory (Digit Span Backward). Adjustment for demographics showed that women with concurrent depressive symptoms scored 1 point lower on the SDMT (P |