Résumé :
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[BDSP. Notice produite par INIST-CNRS 9JloR0xE. Diffusion soumise à autorisation]. Objectives. Meningococcal disease (MD), is a leading cause of meningitis in the U.S. The purpose of this study was to determine the epidemiology of MD in Oklahoma, including trends, high-risk populations, and outcomes. Methods. Cases from the statewide passive reporting system with disease onset between 1988 and 2004 were included ; 2002-2004 cases were linked to hospital discharge data. We performed a multivariate logistic regression of variables predicting death. Results. There were 545 total cases (mean annual incidence rate 1.0/100,000) ; 13% died. Rates were highest for children younger than 2 years of age ; black males had rates two times higher than the state rate and a different age distribution than other race-gender groups. Mean length of hospital stay was 12 days and mean charges were $37,724. For every 10 years of age, the risk of death increased 13% (adjusted odds ratio 1.13,95% confidence interval [CI] 1.05,1.22). People younger than age 40 who developed MD between October and February were 68% more likely to die than those who developed it in other months (rate ratio [RR] 1.68,95% CI 1.39,2.05) ; an increased risk of death during these months was not statistically significant in people aged 40 and older (RR 1.19,95% CI 0.83,1.69). Conclusion. Using statewide public health surveillance data to characterize the epidemiology of MD is important to understand local trends and risk factors.
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