Titre :
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Preterm birth, vascular function, and risk factors for atherosclerosis. (2001)
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Auteurs :
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Atul SINGHAL ;
Tim-J COLE ;
John DEANFIELD ;
M.I.A. KATTENHORN ;
Alan Lucas ;
Department of Vascular Physiology. Institute of Child Health. Guilford Street. London. GBR ;
Mrc Childhood Nutrition Research Centre. Institute of Child Health. Guilford Street. London. GBR
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Type de document :
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Article
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Dans :
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Lancet (The) (vol. 358, n° 9288, 2001)
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Pagination :
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1159-1160
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Langues:
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Anglais
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Mots-clés :
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Prématurité
;
Artériosclérose
;
Facteur risque
;
Etude comparée
;
Epidémiologie
;
Royaume Uni
;
Europe
;
Nouveau né
;
Homme
;
Adolescent
;
Appareil circulatoire [pathologie]
;
Vaisseau sanguin [pathologie]
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Résumé :
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[BDSP. Notice produite par INIST-CNRS R0xt7RKh. Diffusion soumise à autorisation]. Low birthweight may predispose to the development of atherosclerosis later in life. We have tested the hypothesis that low birthweight as a result of preterm birth Is associated with reduced flow-mediated endothellal-dependent vasodilation (FMD), which is an early stage in the development of atherosclerosis. Mean FMD in adolescents born preterm who had a low birthwelght did not differ from that for controls born at term (0.225 mm vs 0.220 mm, SD 0.1 for both means, p=0.78). Our findings indicate that low birthwelght attributable to prematurity does not increase the risk of vascular disease later In life.
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