Titre : | HIV-1 infection and risk of vulvovaginal and perianal condylomata acuminata and intraepithelial neoplasia : a prospective cohort study. (2002) |
Auteurs : | Lois-J CONLEY ; Timothy-J BUSH ; Mary-Ann CHIASSON ; Tedd-V ELLERBROCK ; Dorothy SAWO ; Thomas-C WRIGHT ; Department of Pathology. College of Physicians and Surgeons. Columbia University. New York. NY. USA ; Division of Hiv. Aids Prevention. Surveillance. And Epidemiology. National Center for Hiv. Std. Tb Prevention. Centers for Disease Control and Prevention. Public Health Service. Std. Department of Health and Human Services. Atlanta. GA. USA |
Type de document : | Article |
Dans : | Lancet (The) (vol. 359, n° 9301, 2002) |
Pagination : | 108-113 |
Langues: | Anglais |
Mots-clés : | Sida ; Virose ; Infection ; VIH ; Rétrovirus ; Virus ; Cancer ; Vagin ; Epidémiologie ; Facteur risque ; Homme ; Femme ; Immunopathologie ; Maladie sexuellement transmissible |
Résumé : | [BDSP. Notice produite par INIST-CNRS RSOoR0xj. Diffusion soumise à autorisation]. Background Information about vulvovaginal and perianal condylomata acuminata and intraepithelial neoplasia in women infected with HIV-1 is needed to develop guidelines for clinical J care. Our aim was to investigate the incidence of these lesions in HIV-1-positive and HIV-1-negative women and to examine risk factors for disease. Methods In a prospective cohort study, 925 women had a gynaecological examination twice yearly-including colposcopy and tests for human papillomavirus DNA in cervicovaginal lavage-for a median follow-up of 3.2 years (IQR 0.98-4.87). Endings Vulvovaginal and perianal condylomata acuminata or intraepithelial neoplasia were present in 30 (6%) of 481 HIV-1-positive and four (1%) of 437 HIV-1-negative women (p |