Titre :
|
Childhood, adolescent and early adult body mass index in relation to adult mortality : results from the British 1946 birth cohort. (2012)
|
Auteurs :
|
Bjorn HEINE STRAND ;
Jack GURALNIK ;
Rebecca Hardy ;
Diana KUH ;
Imran SHAH ;
Laboratory of Epidemiology. Demography. And Biometry. National Institute on Aging. National Institutes of Health. Bethesda. MD. USA
|
Type de document :
|
Article
|
Dans :
|
Journal of epidemiology and community health (vol. 66, n° 3, 2012)
|
Pagination :
|
225-232
|
Langues:
|
Anglais
|
Mots-clés :
|
Mortalité infantile
;
Enfant
;
Adolescent
;
Adulte
;
Mortalité
;
Epidémiologie
;
Résultat
;
Grande Bretagne
;
Homme
;
Europe
|
Résumé :
|
[BDSP. Notice produite par INIST-CNRS mGR0xGtD. Diffusion soumise à autorisation]. Background Adult body mass index (BMI) has been consistently related to mortality, but little is known about the impact of earlier life BMI on adult mortality. The aim is to investigate the impact of childhood, adolescent and early adult BMI on premature adult all-cause mortality. Methods The British 1946 cohort study was used to assess the association of BMI in childhood, adolescence and adulthood with mortality 26-60 years (332 deaths). 4462 (83%) respondents were available for analysis at age 26 years. Splines were used in Cox regression to model the associations between BMI and mortality. Results In both genders, adult BMI from 20 years onwards showed a consistent U-shaped relationship with adult mortality (overall p value
|