Titre :
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Impact of rapid screening tests on acquisition of meticillin resistant Staphylococcus aureus : cluster randomised crossover trial. : Impact de tests de dépistage rapide sur l'acquisition de Staphylococcus aureus méticillino-résistant : essai transversal randomisé sur des cas groupés. (2008)
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Auteurs :
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D. JEYARATNAM ;
U. AJOKU ;
G.L. FRENCH ;
D. LIU ;
C. OREZZI ;
K. PHILLIPS ;
C.J. WHITTY
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Type de document :
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Article
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Dans :
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BMJ British medical journal (vol. 336, n° 7650, 2008/04)
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Pagination :
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927-930
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Langues:
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Anglais
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Mots-clés :
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Staphylocoque
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Enquête transversale
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Pharmacorésistance
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Colonialisme
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COLONISATION
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Infection nosocomiale
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Hygiène hospitalière
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Dépistage
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Randomisation
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Taux
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Coût
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Résumé :
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[BDSP. Notice produite par NOSOBASE oR0xHAr9. Diffusion soumise à autorisation]. OBJECTIVE : To determine whether introducing a rapid test for meticillin resistant Staphylococcus aureus (MRSA) screening leads to a reduction in MRSA acquisition on hospital general wards. DESIGN : Cluster randomised crossover trial. SETTING : Medical, surgical, elderly care, and oncology wards of a London teaching hospital on two sites. MAIN OUTCOME MEASURE : MRSA acquisition rate (proportion of patients negative for MRSA who became MRSA positive). PARTICIPANTS : All patients admitted to the study wards who were MRSA negative on admission and screened for MRSA on discharge. INTERVENTION : Rapid polymerase chain reaction based screening test for MRSA compared with conventional culture. RESULTS : Of 9608 patients admitted to study wards, 8374 met entry criteria and 6888 had full data (82.3%) ; 3335 in the control arm and 3553 in the rapid test arm. The overall MRSA carriage rate on admission was 6.7%. Rapid tests led to a reduction in median reporting time from admission, from 46 to 22 hours (P
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