Titre :
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Statistical inference for the area under the receiver operating characteristic curve in the presence of random measurement error. (2001)
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Auteurs :
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Enrique-F SCHISTERMAN ;
David FARAGGI ;
Benjamin REISER ;
Maurizio TREVISAN ;
Department of Social and Preventive Medicine. University at Buffalo. Buffalo. NY. USA ;
Department of Statistics. Haifa University. Haifa. ISR
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Type de document :
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Article
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Dans :
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American journal of epidemiology (vol. 154, n° 2, 2001)
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Pagination :
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174-179
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Langues:
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Anglais
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Mots-clés :
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Cardiopathie
;
Homme
;
Epidémiologie
;
Méthodologie
;
Fiabilité
;
Appareil circulatoire [pathologie]
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Résumé :
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[BDSP. Notice produite par INIST-CNRS 3HoDR0xZ. Diffusion soumise à autorisation]. The area under the receiver operating characteristic curve is the most commonly used measure of the ability of a biomarker to distinguish between two populations. Some markers are subject to substantial measurement error. Under normality assumptions, the authors develop a confidence interval procedure for the area under the receiver operating characteristic curve that adjusts for measurement error. This procedure assumes the availability of data from a reliability study of the biomarker. A simulation study was used to check the validity of the proposed confidence interval. Furthermore, it was shown that not adjusting for measurement error could result in a serious understatement of the effectiveness of the biomarker.
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