Résumé :
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[BDSP. Notice produite par INIST R0xnw3e7. Diffusion soumise à autorisation]. Context Poor muscle strength, functional limitations, and disability often coexist, but whether muscle strength during midlife predicts old age functional ability is not known. Objective To determine whether hand grip strength measured during midlife predicts old age functional limitations and disability in initially healthy men. Design and Setting A 25-year prospective cohort study, the Honolulu Heart Program, which began in 1965 among Japanese-American men living on Oahu, Hawaii. Participants A total of 6089 45-to 68-year-old men who were healthy at baseline and whose maximal hand grip strength was measured from 1965 through 1970. Altogether, 2259 men died over the follow-up period and 3218 survivors participated in the disability assessment in 1991 through 1993. Main Outcome Measures Functional limitations including slow customary walking speed (
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