Titre :
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Diphtheria antitoxin levels in the 14-30-year age group in Italy. (1998)
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Auteurs :
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I. MASTROENI ;
S. BAGNOD ;
S. BOCCHINI ;
C. CIAPETTI ;
G.M. FARA ;
A.M. PATTI ;
A.L. SANTI ;
N. VESCIA ;
Institute of Hygiene'La Sapienza'University of Rome. ITA
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Type de document :
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Article
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Dans :
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European journal of epidemiology (vol. 14, n° 7, 1998)
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Pagination :
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683-686
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Langues:
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Anglais
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Mots-clés :
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Vaccin antidiphtérique
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Vaccination
;
Diphtérie
;
Bactériose
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Infection
;
Examen sérologique
;
Taux
;
Epidémiologie
;
Evaluation
;
Jeune adulte
;
Homme
;
Italie
;
Europe
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Résumé :
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[BDSP. Notice produite par INIST ilV87R0x. Diffusion soumise à autorisation]. In order to verify diphtheria immunity a seroepidemiological survey was performed in 1996-1997. Serum samples were obtained from 501 subjects 14 years old, recruited at 8 schools in Rome, and from 490 subjects 20-30 years old recruited from 15 Italian regions. Serum diphtheria antitoxin was titrated using the Vero cell assay. The minimum protection level of antitoxin was set at 0.01 IU ml-1. The results show that the younger population have a good immunity to diphtheria while a large proportion of young adults is devoid of protective levels of diphtheria antitoxin. Out of the 501 subjects 14 years old. 495 (98.8%) had a diphtheria antitoxin titre >= 0.01 IU ml-1. Only 6 (1.2%) teenagers were susceptible. Out of the 490 subjects 20-30 years old, 109 (22.2%) were susceptible. 381 (77.8%) had a diphtheria antitoxin titre >= 0.01 IU ml-1. The data stress for booster immunization at the end of junior high school.
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