Résumé :
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[BDSP. Notice produite par INIST 0bfR0xY3. Diffusion soumise à autorisation]. Background Studies in Taiwan have found dose-response relations between arsenic ingestion from drinking water and cancers of the skin, bladder, lung, kidney and liver. To investigate these associations in another population, we conducted a study in C6rdoba, Argentina, which has a well-documented history of arsenic exposure from drinking water. Methods Mortality from lung, kidney, liver and skin cancers during the period 1986-1991 in Cordoba's 26 counties was investigated, expanding the authors'previous analysis of bladder cancer in the province. Counties were grouped a priori into low, medium and high arsenic exposure categories based on available data. Standardized mortality ratios (SMR) were calculated using all of Argentina as the reference population. Results We found increasing trends for kidney and lung cancer mortality with arsenic exposure, with the following SMR, for men and women respectively : kidney cancer, 0.87,1.33,1.57 and 1.00,1.36,1.81 ; lung cancer, 0.92,1.54,1.77 and 1.24,1.34,2.16 (in all cases, P
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