Titre :
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A newly identified tick-borne Borrelia species and relapsing fever in Tanzania. (2003)
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Auteurs :
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KISINZA (William-N) : TZA. National Institute For Medical Research. Dar es Salaam. ;
Masahito FUKUNAGA ;
P.J. MCCALL ;
Harumi MITANI ;
TALBERT (Alison) : TZA. Mvuml Hospital. Dodoma. ;
Laboratory of Molecular Microbiology. Faculty of Pharmacy and Pharmaceutical Sciences. Fukuyama University. Fukuyama Hiroshima. JPN ;
Vector Research Group. Liverpool School of Tropical Medicine. Liverpool. GBR
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Type de document :
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Article
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Dans :
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Lancet (The) (vol. 362, n° 9392, 2003)
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Pagination :
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1283-1284
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Langues:
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Anglais
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Mots-clés :
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Bactérie
;
Bactériose
;
Infection
;
Tanzanie
;
Afrique
;
Enfant
;
Homme
;
Epidémiologie
;
Endémie
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Résumé :
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[BDSP. Notice produite par INIST-CNRS 8FR0x4dk. Diffusion soumise à autorisation]. Tick-borne relapsing fever caused by the spirochaete Borrelia duttonii is a common cause of serious illness in central Tanzania. Screening of Ornithodoros sp. ticks from infested houses for the presence of B duttonii had detected a previously unidentified species of Borrelia. We investigated whether this species infected the human population in a central Tanzanian village, by use of blood slide examination and PCR. PCR was twice as sensitive in detection of infections, showing Borrelia sp. in six (11%) of 54 children with fever, and in 13 (4%) of 307 otherwise healthy children. Genotyping Borrelia from 17 infections identified Borrelia duttonii and an unnamed species. Our findings show that the newly discovered species is a causal agent of tick-borne relapsing fever.
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