Titre :
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Carpal tunnel syndrome. A new feature in the natural history of TOS ? (2003)
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Auteurs :
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Eva ESTIRADO DE CABO ;
Beatriz BRAUN SARO ;
Marisa-Lgarcia DE AGUINAGA ;
Pilar DE ANDRES COPA ;
Mar-Del-mar PLAZA CANO ;
Manuel POSADA DE LA PAZ ;
Carmen SUAREZ ALVAREZ ;
Toxic Oil Syndrome and Rare Disease Research Center. Carlos (I.I.I.). Institute of Public Health. Madrid. ESP
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Type de document :
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Article
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Dans :
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European journal of epidemiology (vol. 18, n° 10, 2003)
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Pagination :
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983-993
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Langues:
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Anglais
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Mots-clés :
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Homme
;
Facteur risque
;
Epidémiologie
;
Enquête cas témoin
;
Toxicologie
;
Système nerveux [pathologie]
;
Système ostéoarticulaire [pathologie]
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Résumé :
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[BDSP. Notice produite par INIST-CNRS R0x45U7q. Diffusion soumise à autorisation]. Objective : To ascertain whether carpal tunnel syndrome (CTS) in patients affected with toxic oil syndrome (TOS) is associated with conditions and diseases considered risk factors for CTS in the general population and/or with certain clinical manifestations of TOS. Methods : We conducted a case-control study to compare 89 TOS patients residing in Madrid diagnosed with CTS from 1981 through July 2001 (cases) against 638 TOS patients not affected with CTS (controls). Risk factors for CTS and clinical manifestations of TOS were analyzed. Results : Multivariate logistic regression analysis yielded the following odds ratios (95% confidence interval) : 3.32 (1.47-7.50) for TOS-related neuropathy ; 2.85 (1.14-7.13) for TOS-related thromboembolic events ; 2.63 (1.36-5.06) for female gender ; 0.43 (0.24-0.80) for TOS-related scleroderma ; 0.26 (0.12-0.59) for smoking ; and, in women, 2.53 (1.06-5.70) for fibrositis and 1.84 (1.04-3.20) for miscarriages. Conclusion : Our study findings support the hypothesis that CTS in TOS patients is more linked to certain clinical manifestations of TOS, mainly neuropathy, than to conditions and diseases considered risk factors for CTS in the general population.
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