Résumé :
|
[BDSP. Notice produite par INIST-CNRS qHx1QR0x. Diffusion soumise à autorisation]. Context : Breast augmentation is not associated with an increased risk of breast cancer ; however, implants may interfere with the detection of breast cancer thereby delaying cancer diagnosis in women with augmentation. Objective : To determine whether mammography accuracy and tumor characteristics are different for women with and without augmentation. Design, Setting, and Participants : A prospective cohort of 137 women with augmentation and 685 women without augmentation diagnosed with breast cancer between January 1,1995, and October 15,2002, matched (1 : 5) by age, race/ethnicity, previous mammography screening, and mammography registry, and 10533 women with augmentation and 974915 women without augmentation and without breast cancer among 7 mammography registries in Denver, Colo ; Lebanon, NH ; Albuquerque, NM ; Chapel Hill, NC ; San Francisco, Calif ; Seattle, Wash ; and Burlington, Vt. Main Outcome Measures : Comparison between women with and without augmentation of mammography performance measures and cancer characteristics, including invasive carcinoma or ductal carcinoma in situ, tumor stage, nodal status, size, grade, and estrogen-receptor status. Results : Among asymptomatic women, the sensitivity of screening mammography based on the final assessment was lower in women with breast augmentation vs women without (45.0% [95% confidence interval [CI], 29.3% - 61.5% ] vs 66.8% [95% CI, 60.4% - 72.8% ] ; P=008), and specificity was slightly higher in women with augmentation (97.7% [95% CI, 97.4% - 98.0% ] vs 96.7% [95% CI, 96.6% - 96.7% ] ; P<. among symptomatic women both sensitivity and specificity were lower for with augmentation compared without but these differences not significant. tumors of similar stage size estrogen-receptor status nodal tended to be grade breast vs without. conclusions : decreases the screening mammography asymptomatic does increase false-positive rate. despite accuracy in prognostic characteristics are influenced by augmentation.>
|