Résumé :
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[BDSP. Notice produite par INIST-CNRS 3TAR0xdn. Diffusion soumise à autorisation]. A validation study evaluated the accuracy of self-reported use of commonly used medications among older women. Within a case-control study of breast cancer, drug information was ascertained by interview. Pharmacy records from 1990 to 1999 were obtained from a Washington State health maintenance organization (66% of subjects) and retail pharmacies (34% of subjects) on a sample of subjects (212 cases, 191 controls) and used as the "gold standard." Recall accuracy was assessed for 6-month, 2-year, and 8-year time windows. Sensitivity of antihypertensive use was 92% (95% confidence interval (Cl) : 85,96) for cases and controls in the 6-month period and slightly lower for the 2-year (90% (95% Cl : 82,94) and 87% (95% Cl : 78,92)) and 8-year (80% (95% Cl : 69,88) and 79% (95% Cl : 68,88)) periods. For statins, sensitivity was 83% (95% Cl : 64,93) for cases and 93% (95% Cl : 69,99) for controls in the 6-month period, 75% (95% Cl : 55,88) and 86% (95% Cl : 60,96) in the 2-year period, and 67% (95% Cl : 42,85) and 75% (95% Cl : 41,93) in the 8-year period. For self-report of antidepressants, sensitivities ranged from 66% (95% Cl : 47,80) in the 6-month period to 44% (95% Cl : 30,60) in the 8-year period. Specificity was high among all drug classes, ranging from 91% to 100%. Recall did not differ by case-control status. Trivial changes in estimates were observed when health maintenance organization records alone were used as the gold standard. Self-reported use of antihypertensives and statins appears to be relatively accurate among older women.
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