Résumé :
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[BDSP. Notice produite par INIST-CNRS pR0x0p92. Diffusion soumise à autorisation]. Previous studies have reported declines in high density lipoprotein (HDL) cholesterol 1-2 years after pregnancy. In 1986-1996, the authors prospectively examined the association between childbearing and changes in fasting plasma lipids (low density lipoprotein, HDL, and total cholesterol ; triglycerides) among 1,952 US women (980 Black, 972 White) in the Coronary Artery Risk Development in Young Adults study. Repeated-measures multiple linear regression was used to examine lipid changes over three time intervals (baseline to years 5,7, and 10) in time-dependent follow-up groups : PO (0 pregnancies), P1 (>=1 miscarriages/abortions), B1 (1 birth), and B2 (>=2 births). Means stratified by race and baseline parity (nulliparous or parous) were fully adjusted for study center, time, height, baseline diet, and other baseline and time-dependent covariates (age, smoking, education, weight, waist circumference, alcohol intake, oral contraceptive use, physical activity, short pregnancies). For both races, fully adjusted HDL cholesterol declines of - 3 to - 4 mg/dl were associated with a first birth versus no pregnancies during follow-up (p
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