Résumé :
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[BDSP. Notice produite par INIST-CNRS R0xCB2PW. Diffusion soumise à autorisation]. The authors quantified improvement in predicting cutaneous malignant melanoma, basal cell carcinoma, and squamous cell carcinoma of the skin made possible by information on common variants of the melanocortin-1 receptor gene (MC1R) in a 1998-1999 population-based case-control study of subjects aged 20-59 years of northern European ancestry in Tasmania, Australia. Melanin density at the upper inner arm was estimated by spectrophotometry. DNA samples were genotyped for five MC1R variants : Val60Leu, Asp84Glu, Arg151Cys, Arg160Trp, and Asp294His. Among controls (n=267), variant carriers, versus noncarriers, had lower (p
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