Titre :
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Kidney Disease Mortality and Environmental Exposure to Mercury. (2007)
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Auteurs :
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Susan HODGSON ;
Paul ELLIOT ;
Lars JARUP ;
Mark-J NIEUWENHUIJSEN ;
Imperial College of London. Department of Epidemiology and Public Health. Small Area Health Statistics Unit. London. GBR
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Type de document :
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Article
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Dans :
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American journal of epidemiology (vol. 165, n° 1, Janvier 2007)
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Pagination :
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72-77
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Langues:
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Anglais
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Mots-clés :
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Rein [pathologie]
;
Mortalité
;
Industrie chimique
;
Exposition
;
Mercure
;
Solvant
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Résumé :
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[BDSP. Notice produite par ORSMIP oR0xr9p8. Diffusion soumise à autorisation]. Runcorn, North West England, has been a site of industrial activity for over 100 years. Preliminary investigations have revealed excess risk of renal mortality in the population living closest to several sources of pollution. Exposure to airborne mercury has been highlighted as a possible cause, although there is also concomitant exposure to solvents and other heavy metals in this population. The authors used validated air dispersion modeling to identify mercury-exposed populations. Standardized mortality ratios for kidney disease were computed using the North West government region as the reference. There was a significant exposure-response relation between modeled estimates of mercury exposure and risk of kidney disease mortality (test for trend : p=0.02 for men and p=0.03 for women), and this relation was more pronounced for estimated historical exposure (test for trend : p=0.01 for men and p
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