Titre :
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Are childhood socio-economic circumstances related to coronary heart disease risk ? Findings from a population-based study of older men. Commentary. (2007)
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Auteurs :
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Sheena-E RWNSAY ;
GLYMOUR (Mmaria) / disc. : USA. Department of Epidemiology. Mailman School of Public Health at Columbia University. New York. NY. ;
Lucy-T LENNON ;
Richard-W MORRIS ;
S.G. WANNWNETHEE ;
WHINCUP (Peter-H) : GBR. Department of Community Health Sciences. St George's University of London. London. ;
Department of Primary Care and Population Sciences. Royal Free Hospital and University College Medical School. London. GBR
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Type de document :
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Article
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Dans :
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International journal of epidemiology (vol. 36, n° 3, 2007)
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Pagination :
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560-568
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Langues:
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Anglais
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Mots-clés :
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Cardiopathie coronaire
;
Facteur risque
;
Epidémiologie
;
Facteur socioéconomique
;
Royaume Uni
;
Adulte
;
Europe
;
Homme
;
Appareil circulatoire [pathologie]
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Résumé :
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[BDSP. Notice produite par INIST-CNRS 6EoR0xG6. Diffusion soumise à autorisation]. Background The independent influence of childhood social circumstances on health in later life remains uncertain. We examined the extent to which childhood socio-economic circumstances are related to the risk of coronary heart disease (CHD) in older British men, taking account of adult social class and behavioural risk factors. Methods A socio-economically representative sample of 5552 British men (52-74 years) with retrospective assessment of childhood socio-economic circumstances (father's occupation and childhood household amenities) who were followed up for CHD (fatal and non-fatal) for 12 years. Results Men whose childhood social class was manual had an increased hazard ratio (HR) 1.34 (95% CI 1.11-1.63) - this effect was diminished when adjusted for adult social class and adult behavioural risk factors (cigarette smoking, alcohol, physical activity and body weight) (HR 1.19 ; 95% CI 0.97-1.46). Men whose family did not own a car in their childhood were at increased CHD risk even after adjustments for adult social class and behaviours (HR 1.35,95% CI 1.04-1.75). Men with combined exposure to both childhood and adult manual social class had the highest risk of CHD (HR 1.51 ; 95% CI 1.19-1.91) ; this was substantially reduced by adjustment for adult behavioural risk factors (adjusted HR 1.28 ; 95% CI 0.99-1.65). Conclusions Less affluent socio-economic conditions in childhood may have a modest persisting influence on risk of CHD in later life.
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