Résumé :
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[BDSP. Notice produite par INIST KaR0xyMF. Diffusion soumise à autorisation]. Objectives To assess whether different definitions of acute coronary events yielded concordant results concerning trends and geographical disparities in coronary heart disease (CHD) mortality and morbidity in France. Study Data from three French CHD registries participating in the WHO MONICA Project design during the period 1985-1992. Setting Three areas of about one million inhabitants each in the North, South and East of France. Subjects About 2000 acute coronary events each year. Main Mortality, annual rate of fatal and non-fatal events, incidence of first and outcome recurrent events, case-fatality rates. measures Results For incidence and mortality, the broader the definition of the acute event, the higher the reported rates. The same tendency was not observed for case-fatality rates. Comparing between-registry rates for mortality, 28-day case-fatality and hospital case fatality yielded relatively concordant results whatever the definition of event. As a whole, the higher mortality rate in Lille and its intermediate rank in Strasbourg were related more to disparities in case-fatality rates, with only small variations in incidence rates, independently of the definition used. Comparing temporal trends in rates within and between regions, a consistent decrease in annual mortality rates and case-fatality rates was observed, whatever the definition. In contrast, the incidence of non-fatal probable myocardial infarction did not change during the period in any register. (...)
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