Résumé :
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[BDSP. Notice produite par INIST Pw2zR0x4. Diffusion soumise à autorisation]. Studies of low to moderate level lead exposures have reported mixed findings regarding the risk of spontaneous abortion, despite lead's abortifacient properties at very high doses. To evaluate the risk of spontaneous abortion from low or moderate lead exposures, a nested case-control study was conducted within a cohort of pregnant women in Mexico City, 1994-1996. During their first trimester, 668 women enrolled, were interviewed, and contributed blood specimens. Pregnancies were followed by home visits or telephone calls. Spontaneous abortions before week 21 (n=35) were matched with pregnancies that survived beyond week 20 (n=60) on maternal age, hospital, date of enrollment, and gestational age at enrollment. Mean blood lead levels were 12.03 mug/dL for cases and 10.09 mug/dL for controls (p=0.02). Odds ratios for spontaneous abortion comparing 5-9,10-14, and >=15 mug/dL with the referent category of
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