Titre :
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Natural Haemophilus influenzae type b capsular polysaccharide antibodies in 412 infants and children from West Africa (Burkina-Faso) and France : A cross-sectional serosurvey. (1999)
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Auteurs :
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F. BALLEREAU ;
V. APAIRE-MARCHAIS ;
M. SPEICH ;
Département de Santé Publique et de Pharmacie Clinique. Faculté de Pharmacie. Université de Nantes. Nantes. FRA
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Type de document :
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Article
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Dans :
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European journal of epidemiology (vol. 15, n° 6, 1999)
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Pagination :
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577-582
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Langues:
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Anglais
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Mots-clés :
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Vaccination
;
Bactérie
;
Programme élargi vaccination
;
Programme santé
;
Epidémiologie
;
Evaluation
;
Etude comparée
;
Nourrisson
;
Homme
;
Enfant
;
Burkina Faso
;
Afrique
;
France
;
Europe
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Résumé :
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[BDSP. Notice produite par INIST vR0x2o5D. Diffusion soumise à autorisation]. Prior to possible introduction of large-scale vaccination programmes, an estimation and comparison of naturally acquired immunity against Haemophilus influenzae type b (Hib) was carried out in two populations of age-stratified infants and children (from birth to 14 years old) in Burkina-Faso (West Africa) (n=206) and France (n=206). Hib capsular polysaccharide antibodies were detected by an ELISA method. The difference in the percentages of minimum protective levels for the two populations were not significant (0.15 mug/ml) for newborns (0-1 month) but became significant as early as 2 to 3 months of age (p=0.15 mug/ml were significantly higher in France (p1.0 mug/ml before one year of age. Thereafter, only 9.51% of French children in the 12-to 17-month age stratum and 19.2% over 4 years of age had antibody levels>1.0 mug/ml. (...)
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