Résumé :
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[BDSP. Notice produite par INIST P6cR0xgz. Diffusion soumise à autorisation]. The authors investigated the relation between physical activity and cardiovascular disease (CVD) in women by following 1,564 University of Pennsylvania alumnae (mean age, 45.5 years), initially free of CVD, from 1962 until 1993. Energy expenditure was estimated from the daily number of flights of stairs climbed and blocks walked as well as the sports played and was categorized into approximate thirds (=1,000 kcal/week). During 35,021 person-years, 181 CVD cases were identified. After adjustment for coronary risk factors, the relative risks of CVD were 0.99 (95% confidence interval (Cl) : 0.69,1.41) and 0.88 (95% Cl : 0.62,1.25) for women who expended 500-999 and >=1,000, respectively, compared with=10 blocks/day, respectively. Finally, an interaction (p=0.023) between body mass index and physical activity on CVD risk was observed, with an inverse association only for leaner (=10 blocks/day (approximately 6 miles (9.7 km)/week) was associated with a 33% decreased risk. (...)
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