Résumé :
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[BDSP. Notice produite par INIST-CNRS zCgR0xEU. Diffusion soumise à autorisation]. Simple, robust approaches are needed to monitor prevalence, Incidence, and mother-to-child transmission of HIV-1 In rural Africa. We have designed a method that uses antibody and viral RNA testing of dried blood spots obtained from mother-Infant pairs attending routine Immunisation clinics. In our study, prevalence and Incidence of HIV-1 was highest In young women In their late teens and early twenties. In children bom to Infected mothers, prevalence increased from 14% in Infants younger than 6 weeks of age to 24% at 3-6 months. The blood-spot approach Is an effective method for surveillance of HIV-1 in women and children, and for early Identification of incidence of this Infection In women of child-bearing age.
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