Titre :
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Smoking-Related Health Risks Among Persons With HIV in the Strategies for Management of Antiretroviral Therapy Clinical Trial. (2010)
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Auteurs :
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Alan-R LIFSON ;
Jose-Ramon ARRIBAS ;
Ann-M LABRIOLA ;
Jacqueline NEUHAUS ;
Timothy-Rh READ ;
Mary VAN DEN BERG-WOLF
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Type de document :
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Article
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Dans :
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American journal of public health (vol. 100, n° 10, 2010)
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Pagination :
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1896-1903
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Langues:
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Anglais
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Mots-clés :
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Tabagisme
;
Sida
;
Tabac
;
VIH
;
Stratégie
;
Thérapeutique
;
Médicament antirétroviral
;
Traitement antirétroviral
;
Médicament antiviral
;
Thérapeutique médicamenteuse
;
Chimiothérapie
;
Essai thérapeutique
;
Virose
;
Infection
;
Rétrovirus
;
Virus
;
Immunopathologie
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Résumé :
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[BDSP. Notice produite par INIST-CNRS FCp98R0x. Diffusion soumise à autorisation]. Objectives. We sought to determine smoking-related hazard ratios (HRs) and population-attributable risk percentage (PAR%) for serious clinical events and death among HIV-positive persons, whose smoking prevalence is higher than in the general population. Methods. For 5472 HIV-infected persons enrolled from 33 countries in the Strategies for Management of Antiretroviral Therapy clinical trial, we evaluated the relationship between baseline smoking status and development of AIDS-related or serious non-AIDS events and overall mortality. Results. Among all participants, 40.5% were current smokers and 24.8% were former smokers. Adjusted HRs were higher for current than for never smokers for overall mortality (2.4 ; P<. major cardiovascular disease p="002)," non-aids cancer and bacterial pneumonia adjusted hrs also were significantly higher for these outcomes among current than former smokers. the par versus never smokers combined was overall mortality pneumonia. conclusions. smoking contributes to substantial morbidity in this hiv-infected population. providers should routinely integrate cessation programs into hiv health care.>
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