Résumé :
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[BDSP. Notice produite par INIST-CNRS gR0xMQ6t. Diffusion soumise à autorisation]. Studies associate alcohol consumption, cigarette smoking, and body size with the risk of overall or subtype lymphoma. Current data come mostly from case-control studies or prospective studies with few cases. In the prospective National Institutes of Health-former American Association of Retired Persons (NIH-AARP) Diet and Health Study, the authors assessed the above lifestyle factors via baseline questionnaire among 285,079 men and 188,905 women aged 50-71 years and ascertained histologically confirmed Hodgkin's lymphoma (n=58) and non-Hodgkin's lymphoma (n=1,381) cases through linkage with cancer registries from 1995 to 2000. Compared with nondrinkers, alcohol consumers had a lower risk for non-Hodgkin's lymphoma overall (for>28 drinks/week : adjusted relative risk (RR)=0.77,95% confidence interval (Cl) : 0.59,1.00 ; Ptrend among drinkers=0.02) and for its main subtypes. Compared with never smokers, current smokers and recent quitters (35 : RR=1.29,95% Cl : 1.02,1.64) and taller height (RR=1.19,95% Cl : 1.03,1.38) were associated moderately with non-Hodgkin's lymphoma. These findings add to the evidence that lifestyle factors and relevant anthropometric characteristics play a role in lymphoma etiology.
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