Résumé :
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[BDSP. Notice produite par INIST-CNRS 9kl99R0x. Diffusion soumise à autorisation]. Background/aims : Childhood cognition predicts adult morbidity and mortality, potentially working through health behaviours. This study investigates if childhood cognition influences life course (i) non-drinking and (ii) binge drinking and pathways through which this might act-namely, childhood behaviour problems, adult social position and educational qualifications. Methods : Prospective cohort of British births in March 1958, with information on cognition at 7,11 and 16 years and alcohol use at 23,33 and 42 years. Non-drinkers drank "infrequently/on special occasions" or "never". Binge drinkers consumed>=10 units/occasion (men) and>=7 units/occasion (women). Results : Lower cognitive ability increased the odds of non-drinking at each adult survey (for example, for men at 42 years OR 1.52 (95% Cl 1.34 to 1.72) per SD decrease in 7-year maths). Associations remained after adjustment for pathway factors (i) behaviour problems, (ii) adult social position and (iii) educational qualifications. Decreased ability rank across childhood (7-16 years) also increased odds of non-drinking at 42 years, but the association operated via pathway factors. Lower 7-year ability elevated the odds of 42-year binge drinking, operating via pathway factors. Declining ability rank across childhood also increased the odds of adult binge drinking ; associations operated through behavioural problems, adult social position and qualifications. In women, the decline in risk of binge drinking from an age 23-year peak to 42 years was associated with higher 7-year score. Conclusions : Poorer childhood cognition was associated with non-drinking and binge drinking up to the early 40s. Associations between childhood cognition and drinking status may mediate between childhood cognition and adult health.
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