Titre :
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The non-cancer mortality experience of male workers at British Nuclear Fuels plc, 1946-2005. Commentary. (2008)
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Auteurs :
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Dave MCGEOGHEGAN ;
Keith BINKS ;
Sarah-C DARBY, disc. ;
Michael GILLIES ;
Steve JONES ;
Paul MCGALE, disc. ;
Steve WHALEY ;
Clinical Trial Service Unit. Richard Doll Building. University of Oxford. Oxford. GBR ;
Westlakes Scientific Consulting. Moor Row. Cumbria. GBR
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Type de document :
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Article
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Dans :
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International journal of epidemiology (vol. 37, n° 3, 2008)
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Pagination :
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506-523
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Langues:
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Anglais
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Mots-clés :
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Rayonnement ionisant
;
Exposition professionnelle
;
Facteur socioéconomique
;
Mortalité
;
Epidémiologie
;
Homme
;
Europe
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Résumé :
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[BDSP. Notice produite par INIST-CNRS AII7R0xE. Diffusion soumise à autorisation]. Background Recent studies of the Hiroshima and Nagasaki A-bomb survivors, together with some (but not all) cohorts exposed occupationally or medically to ionizing radiation, have found an increasing trend in mortality from non-malignant disease with increasing radiation dose. The aim of this study was to establish whether such a trend could be found in a large cohort of employees in the UK nuclear industry. Methods The cohort comprised 64 937 individuals ever employed at the study sites between 1946 and 2002, followed up to 2005 ; radiation exposures as measured by personal dosimeters ('film badges') were available for 42426 individuals classified as'radiation workers'Poisson regression models were used to investigate the relationship between excess mortality rates and cumulative radiation exposure, using both relative and additive risk models. Results The cohort shows a pronounced'healthy worker'effect. Overall, socio-economic status as indicated by employment status has a greater influence on mortality than does radiation exposure status. For male radiation workers, there is an apparent dose response for mortality from circulatory system disease [P
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