Résumé :
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[BDSP. Notice produite par INIST-CNRS qD2R0xi1. Diffusion soumise à autorisation]. Currently lacking are stable and easily measured biomarkers that can reflect oxidative stress in humans. Fluorescent oxidation products may fulfill all three of these criteria. Fasting plasma levels of fluorescent oxidation products were measured in 286 controls in a study of coronary heart disease among US men aged 47-81 years ; the study concluded in 2006. Other biomarkers in plasma were also measured, and cardiovascular risk factors such as smoking, hypertension, age, and physical activity were assessed by questionnaire. Indicators of oxidative stress, including smoking, hypertension, and reduced renal function, were associated with greater fluorescent oxidation products in both age-and multivariate-adjusted analyses (for each, p for trend
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