Titre :
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Uptake of screening and prevention in women at very high risk of breast cancer. (2001)
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Auteurs :
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D.G.R. EVANS ;
C. BOGGIS ;
A. HOWELL ;
F. LALLOO ;
A. SHENTON ;
Department of Medical Genetics. St Mary's Hospital. Manchester. GBR
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Type de document :
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Article
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Dans :
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Lancet (The) (vol. 358, n° 9285, 2001)
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Pagination :
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889-890
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Langues:
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Anglais
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Mots-clés :
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Sein
;
Dépistage
;
Prévention santé
;
Femme
;
Homme
;
Cancer
;
Glande mammaire [pathologie]
|
Résumé :
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[BDSP. Notice produite par INIST-CNRS TOR0x5F6. Diffusion soumise à autorisation]. Management of women at high lifetime risk of familial breast cancer is hampered because of limited data concerning the appropriateness of treatment options. Over the past 8 years women at very high (>40%) lifetime risk of breast cancer have had the option of entering two chemopreventlon treatment trials, a magnetic resonance Imaging (MRI) breast screening study, or a risk-reducing mastectomy (RRM) study. Only 10% of eligible women have entered one of the chemotherapy trials with a similar proportion opting for RRM (>50% in mutation carriers) compared with 60% opting for MRI screening. Future chemotherapy trials will have to be designed to address this poor recruitment.
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